A yellow snow and ice warning has also been issued across Scotland with as much as 10cm in places.
The alert comes into force at 4pm on Thursday and remains in place until midday on Friday.
The Met Office has said snow showers and icy roads could lead to travel disruption.
Some roads and railways are likely to be affected with longer journey times by road, bus and train services.
The forecaster also warned of injuries from slips and falls.
Snow on high ground is expected to start to fall to low levels through Thursday evening and overnight.
On low ground, 1 to 2cm is possible by Friday morning, while on hills above 300 metres there is likely to be accumulations of 2 to 5cm.
The Met Office said 10cm of snow was possible in some places.
Temperatures will fall quickly, and this is likely to lead to ice on untreated surfaces.
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